No - A visa is not required for travel to Vatican City (Holy See)

Wednesday, April 8, 2020

Please refer to the visa requirements for Italy.

Register your trip with the US Embassy:

The US State Department strongly encourages American citizens planning international travel to register with the US Embassy(s) in the countries they plan to visit. For just $20.00 per traveler, Travisa will complete the State Department Registration for the applicant. Official notifications about travel advisories and warnings will be sent to the traveler registered.

Click here to register your trip with the US Embassy in Vatican City (Holy See)